Bruno Nunes
Human and environmental health: historical and predictive perspective in the area of Estarreja using combined methodologies
The assessment of human toxicity is a task that is encompassed by ethical constraints. On the contrary, toxicity data from wild organisms, especially invertebrate species, do not require the approval of special authorizations; even for the use of vertebrates, the adoption of ethical standards allows obtaining valid data. Humans and wild animals have long shared common specific features that have conditioned in the past their physiology, leading frequently to the establishment of chemical toxicity. Therefore, the effects of such chemicals that might occur in impacted areas, such as Estarreja, may be analyzed by comparing health data for humans, and toxic profiles for wild animals, that co-occur in the same environment. The use of a retrospective approach, by analyzing the incidence and prevalence of diseases that are likely to be environmentally-related (such as hypertension, renal failure, abnormal heart conditions, and neurodegenerative conditions) may be quantified by comparing the evolution in the profile of the use of pharmaceutical drugs by the population at Estarreja. This profile may be then compared with profiles of human drug consumption, both at national and local levels, to evaluate increased incidences and prevalences of pathological conditions among the Estarreja human population. Furthermore, and considering that such pathologies are environmentally-related, it is possible to assume that similar occurrences may be also present in wild organisms, namely domestic and aquatic animals. In this case, their capture, sacrifice and organ analysis, may reveal the present and past of the toxicological profile of chemical contamination in Estarreja area.
Projet OHMs
OHM(s) concerné(s)
  • Estarreja
Biochimie, Biologie, Chimie, Écologie de la santé, Écophysiologie, Santé publique