Porteur
Ana Moreira
Session
2019
Co-porteur(s)
Ana Sousa, Elisabete Costa, Ana Lillebø, Ricardo Calado, Manuel Coimbra, Pedro Domingues, Rosário Domingues
Titre
Valorization of Ria de Aveiro macroAlgae as a source of lipids with potential health benefits (ValoRiAlga)
Résumé
Macroalgae are a rich source of high nutritional value and health-promoting compounds, including glycolipids that have been related to the prevention of cardiovascular and neurodegenerative diseases and tumor progression, among other potential health benefits. Previous studies showed that the biochemical composition and, in particular, the fatty acid profile of macroalgae are species specific and sensitive to environmental conditions. The shifts in the lipidome of macroalgae may change their nutritional value, as well as their bioactive properties and potential applications. Thus, in the context of the OHMI-Estarreja (2019) research topics “Public health” and “Biodiversity Evolution”, in line with the RIS3-Centro priority and with Estarreja Strategic Development Plan 2015-2025 – “Protect and enhance the natural resources”, ValoRiAlga project aims to study biochemical composition, lipid profile and lipids bioactivity of macroalgae from Ria de Aveiro lagoon, addressing geographical and seasonal variability. To reach this goal, ValoRiAlga team, involving Biochemists, Biologists, Industrial Chemist, and Pharmaceutical Scientists, will investigate the most representative macroalgae genus at Ria (green Ulva and red Gracilaria), which will be collected in Summer and Winter at Ílhavo, Mira, Espinheiro and São Jacinto-Ovar channels. As we can only ‘protect and enhance’ what we know, the generated science-based knowledge will support a sustainable exploitation of this ‘natural resource’. Results will be broadly disseminated and play a key role in the local, national and international valorisation of Ria de Aveiro macroalgae, enhancing the social valorization of macroalgae and derivatives, but also their market value for health promotion and potential cosmeceutical, nutraceutical and pharmaceutical applications.
Type
Projet OHMs
OHM(s) concerné(s)
  • Estarreja
Disciplines
Biochimie, Chimie
Image

Porteur

Ana
Moreira
Ana S. P. Moreira (https://orcid.org/0000-0003-4745-0984) received her first degree in Biochemistry in 2009, her Master in Analytical Chemistry and Quality in 2011, and her PhD degree in Biochemistry in 2016, all at the University of Aveiro (UA, Portugal). Presently, she is Post-Doc at the Mass Spectrometry Centre (Department of Chemistry, UA) in the framework of the project GENIALG - GENetic diversity exploitation for Innovative macro­ALGal biorefinery, funded by European Union’ s Horizon 2020. Since 2012, she has been conducted research work in the field of structural characterization of different biomolecules, specially carbohydrates and lipids, from different matrices, using glycomics and lipidomics approaches. During this 5-years period, she has been working with different mass spectrometers, also coupled to liquid and gas chromatography apparatus, developing excellent skills in analysis of mass spectrometry data. During her PhD, she performed a one-month research work in the Institute of Food Science, Technology and Nutrition (lCTAN-CSIC, Madrid, Spain), gaining experience in some cell biology techniques. She is first author and co-author of 32 articles in international journals with referees , 4 book chapters, 29 oral communications, and 28 communications as poster. She was a member of the organizing committee of 2 international conference and 10 national meetings. She has won 5 prices, supervised 7 first degree students, and was referee of 14 papers from international journals.

Participants

Ana
Moreira
Ana S. P. Moreira (https://orcid.org/0000-0003-4745-0984) received her first degree in Biochemistry in 2009, her Master in Analytical Chemistry and Quality in 2011, and her PhD degree in Biochemistry in 2016, all at the University of Aveiro (UA, Portugal). Presently, she is Post-Doc at the Mass Spectrometry Centre (Department of Chemistry, UA) in the framework of the project GENIALG - GENetic diversity exploitation for Innovative macro­ALGal biorefinery, funded by European Union’ s Horizon 2020. Since 2012, she has been conducted research work in the field of structural characterization of different biomolecules, specially carbohydrates and lipids, from different matrices, using glycomics and lipidomics approaches. During this 5-years period, she has been working with different mass spectrometers, also coupled to liquid and gas chromatography apparatus, developing excellent skills in analysis of mass spectrometry data. During her PhD, she performed a one-month research work in the Institute of Food Science, Technology and Nutrition (lCTAN-CSIC, Madrid, Spain), gaining experience in some cell biology techniques. She is first author and co-author of 32 articles in international journals, 4 book chapters, 29 oral communications, and 28 communications as poster. She was a member of the organizing committee of 2 international conference and 10 national meetings. She has won 6 prices, supervised 7 first degree students, and was referee of 14 papers from international journals.
Ana
Sousa
Ana I. Sousa (Researcher at Biology Department and CESAM, University of Aveiro) holds a PhD in Biology (University of Lisbon, 2010), MSc in Ecology and BSc in Biology (University of Coimbra). She has (co-)authored 20 ISI-indexed papers (h-index=10; Citations: 532; detailed CV: www.cesam.ua.pt/anaisousa). AISousa has a research background in marine ecology and ecosystems functioning. Her main research interests include ecosystem services provided by wetlands; climate change and anthropogenic impacts on coastal wetlands, and wetlands restoration. AISousa expertise domains include marine primary producers’ ecology (halophytes, seagrasses and macroalgae). Aiming macroalgae, she focused on ecology, ecophysiology and taxonomy, i.e., performed macroalgae phycocolloids’ extraction, contributed to MACOI-collection-Portuguese-Seaweeds-Website (University of Coimbra), got expertise on “Marine Algae” (University of Washington, USA, 2007), and studied physico-chemical parameters affecting Ulva intestinalis reproduction. Since 2012, AISousa has developed research at Ria de Aveiro coastal lagoon, mainly focused on wetlands’ functioning, through the participation in (inter-)national projects. She is a team member of PORBIOTA (FCT-PT) and eLTER (H2020) projects, which presents Ria de Aveiro as a case study. AISousa participated in the LAGOONS (EU-FP7) and LTER–RAVE projects (FCT-PT), was the coordinator of MARSH-C-LEVEL and C-GRASS projects (CNRS/OHMI-2015&2017) and was a team member of RESTORE and SOILSALT projects (CNRS/OHMI-2016&2017). She is the co-coordinator of BioPradaRia project (MAR2020), the PI at UAveiro of the GLOW-Global Wetlands international project (AU), and participates in the CtLight project (FCT-PT), focused on the optimized growth of a macroalgae (FCT-PT). Most of these projects have Ria de Aveiro and/or Baixo Vouga Lagunar as case studies.
Elisabete
Costa
Elisabete da Costa has graduated in Industrial Chemistry (University of Coimbra), received her MSc in Instrumental Methods and Analytical Control (University of Aveiro), and holds a Ph.D. in Sustainable Chemistry entitled "High added value products from macroalgae: lipids as bioactive compounds" (University of Aveiro in collaboration with ALGAPlus company, 2018). Following the industrial career at Grupo PortucelSoporcel and RAIZ, where she get expertise in wood, pulp and paper science and analytical methods pointing out infrared spectroscopy approaches, she started her scientific career in 2010 at the University of Aveiro (CICECO/QOPNA/Centre of Mass Spectrometry). She is pursuing a Post-Doctoral Research Fellow within framework of the project GENIALG – Genetic diversity exploitation for innovative macro-alga biorefinery (ANR-15-MRSE-0015) funded by European Union’s Horizon 2020 Framework Programme. The most current research interests include lipidomics of macroalgae and other marine organisms (by using mass spectrometry approaches and green methodologies), the evaluation of the biological function of algal lipids as high-value active ingredients products for therapeutics and nutraceutics and the smart and integral valorisation of macroalgae. She published fifteen original international publications and one national publication, delivered seventeen oral and eleven poster communications in several national and international scientific meetings, a book chapter in "Seaweed Bioactives", and has been a member and researcher in national and international projects and several workshops/showcases promoting Mass Spectrometry, Chemistry and the Valorisation of Macroalgae. She has participated as a trainer in courses of specialization within doctoral programmes and in the guidance of Master and undergraduate student.
Ana
Lillebø
Ana Lillebø (Principal Researcher at the Department of Biology & CESAM, University of Aveiro) holds a Ph.D. in Biology, University of Coimbra, 2001, Portugal. She has considerable research experience in coastal systems ecology, anthropogenic impacts and environmental chemistry (115 ISI-indexed publications, including several papers on salt marshes ecology and Ria de Aveiro; h-index=26, Researcher ID: C-3773-2009), but also has interests in marine ecosystem services, nature-based solutions in applied ecology and integrated coastal management strategies. Presently, she is the Scientific Coordinator of CESAM - Centre for Environmental and Marine Studies (www.cesam.ua.pt). She coordinated the LAGOONS (EU/FP7) project, was the PI for UA in the ADAPT-MED (EU/FP7/ CIRCLE-MED Era Net) project, was a team member in the RESTORE, MARSH-C-LEVEL, HALOFOOD, C-GRASS and SOILSALT (CNRS/INEE, via OHMI) projects, and case study leader in the AQUACROSS (EU/H2020) project. All above-mentioned projects have Ria de Aveiro and/or Baixo Vouga Lagunar as case study. She is also a team member in the GENIALG (EU/H2020) project, which aims support the production and sustainable exploitation of macroalgae. Ana Lillebø detailed CV is available athttp://www.cesam.ua.pt/ana-lillebo
Ricardo
Calado
Ricardo Calado, born in 1976, obtained his PhD in 2005 in Biology (specialization in Animal Biotechnology) from the Faculty of Sciences of Lisbon University (FCUL). From 2013 he is Principal Researcher at the Department of Biology (dbio) and the Associated Laboratory CESAM of University of Aveiro (UA). He develops independent research on Sustainable Blue Growth, namely in the research fields of Applied Marine Ecology, Sustainable Aquaculture and Marine Biotechnology. Author of 171 publications listed on Web of Science (WoS), he has +2300 citations, an h-index of 25 and an accumulated impact factor +500. Currently he supervises/co-supervises 3 MSc (31 completed) and 8 PhD students (14 completed), 6 Post-docs (8 completed) and 5 technicians ( 2 with PhD and 3 with MSc) (3 with PhD, 10 with MSc and 1 with BSc completed). He is/has already been responsible as PI of research projects adding up to > 1.5M euros, several of them in consortium with SMEs. He is the responsible of CESAM’s theme line entitled Marine Ecosystem Resources, co-coordinates the Marine Technology Platform of UA and is the vice-head of dbio at UA.
Manuel
Coimbra
Manuel A. Coimbra born in 1963. He is Associated Professor, PhD in Chemistry (University of Aveiro – 1993), with Habilitation in Chemistry and Professor of Biochemistry and Food Chemistry of the University of Aveiro. Director of the BSc in Biochemistry of the Universidade de Aveiro, since 17/11/2006. President of the Scientific Panel of Food Additives and Contaminants of the Food Chain of ASAE, the Portuguese Food Safety Agency, since 2008Principal Researcher and/or Participant in several research projects funded by different European and Portuguese entities, including FCT (PRAXIS, POCTI, POCI) e Ministry of Agriculture (PAMAF, AGRO), QREN, INTERREG, among others, accounting for 2.5 M€ to UAVR. Collaboration with industries, including Portuguese and international, in the area of food industries, with an income of 0.5 M€ to UAVR. Associate Editor of Carbohydrate Polymers, Elsevier, since September 2011. Supervisor of 18 PhD students (thesis concluded). Co-author of 4 patents and more than 200 papers (until 2019) in peer reviewed journals in the areas of food chemistry and biochemistry, carbohydrate chemistry, polysaccharides chemistry, volatile compounds, phenolic compounds and biological activities of these compounds, and with expertise on the structural and functional characterization of carbohydrate chemistry. Researcher of QOPNA Research Unit of the University of Aveiro.
Pedro
Domingues
Pedro Domingues is presently assistant professor with aggregation at Aveiro mass spectrometry centre at University of Aveiro, Portugal. He received his BA in Pharmaceutical Sciences at the University of Coimbra in 1990 and his PhD in Chemistry- Mass Spectrometry at Aveiro University in 2000. He has been working in mass spectrometry applications since 1996. His research is concerned with applications of mass spectrometry for the study of oxidative stress. Main work has been developed in the detection and characterization of free radicals by mass spectrometry, the study of oxidative stress in lipids and phospholipids and proteins. Currently, his special interests are the study and characterization of oxidized lipids, peptides and proteins using mass spectrometric approaches. He is author or co-author of more than 180 publications. He was the Director of the Master in Biomolecular Methods of the University of Aveiro (2007-2009) and the Director of the Master in Biochemistry of the University of Aveiro (2010-2018) and member of the Pedagogical Board of the University of Aveiro Currently he is member of the board of the Portuguese Biochemistry Society and co-ordinator of the mass spectrometry group of the Chemistry Department, UA. Orcid ID: 0000-0002-8060-7675 ResearcherID: E-5202-2010
Rosário
Domingues
Rosário Domingues is graduated in Pharmaceutical Sciences, University of Coimbra (1990), received her Ph.D. degree in Chemistry (1998), and Habilitation in Biochemistry (2014), from the University of Aveiro (UA). Since 2014, she helds the contract of Assistant Professor with Habilitation in the Mass Spectrometry Centre of the Department of Chemistry (UA). She has over 25 years of research experience in the field of mass spectrometry, as specialist in lipidomics, glycomics and changes in biomolecules associated with oxidative stress. She participated in several juries of academic examinations, scientific committees of congresses, and in the supervision of 12 Post-Docs, 20 Ph.D. and 60 M.Sc. students. She coordinated and participated in several research projects funded by national and European programs (18 in total), has authored 1 book and 6 book chapters, and has over 225 articles published in international journals with referee.